I was looking at this guitar since I've had such great experience with Sire's Marcus Miller basses which have been impeccable. I can wholeheartedly recommend this guitar. The look, the finish, the playability is outstanding. From the two single-coils I get a sweet classic Strat sound, and then I have the humbucker on top of that. Factory setup was flawless. I haven't changed a thing. In fact, it was so well setup and playable with its 10/46 factory strings that, after 40+ years of playing with 9/42 strings, Sire has made me want to try 10/46 on a few more guitars.
I have two other guitars twice the price of this one, and another two that are at least 1000 EUR more expensive, and the S10 HSS is just as good as those four guitars. I love them all, but this was a very good purchase.
I would consider buying a second one if they'd release burl top S10's in some additional colours. Transparent deep purple, perhaps?